First set zoom to 120% in Settings Zoom. Use
Fixed Zoom add on for easy access.
Set fonts in Preferences, fonts and colours. Don't forget to adjust minimal font size in Advanced and untick "Allow pages to choose their own fonts, instead of your selections above".
Make a Chrome folder in your home/username/.mozilla folder. Download template
here and paste in userContent.css:
* {
line-height: 2em !important;
}
html, body, div, section, article, p, span, th, td {
line-height: 2em !important;
}
This helps to prevent problems with line spacing.